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Clinical evaluation of platelet-rich plasma and bioactive glass in the treatment of intra-bony defects (Demir, Becen.)

Bibliographical information (record 264368)

Clinical evaluation of platelet-rich plasma and bioactive glass in the treatment of intra-bony defects
Author:	Demir, Becen. Search Author in Amazon Books
Publisher:	Blackwell publishing,

Edition:	2007.
Classification:	WU 29
URL:	http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1111/j.1600-051X.2007.01108.x

Detailed notes

- Background: There are limited numbers of studies focused on the using of platelet-rich plasma (PRP) combined with different types of bone substitutes in intra-bony defects. Aim: The purpose of this study was to evaluate the effect of bioactive glass graft material (BG) with and without PRP on the clinical healing of intra-bony defects. Materials and Methods: Twenty-nine intra-bony defects were randomly treated with either PRP/BG or BG alone. Clinical parameters were recorded at baseline and repeated 9 months after surgery and surgical reentries were also performed. Results: The results showed that both treatment modalities were effective. Pocket depth reduction of 3.60 +/- 0.51 mm, clinical attachment gain of 3.3 +/- 1.77 mm and defect fill of 3.47 +/- 0.53 mm were noted in the PRP/BG group, with 3.29 +/- 1.68, 2.86 +/- 1.56 and 3.36 +/- 0.55 mm improvements, respectively, noted for the BG group. None of the differences between the two treatment modalities were statistically significant. Conclusions: It is suggested that both PRP/BG combination and BG alone are effective in the treatment of intra-bony defects. The results also showed that using PRP with BG has no additional benefit in the reduction of pocket depth, clinical attachment gain and defect fill.