a Record control number 000245852400013

a ISSN 0931-041X

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number WJ300

b Item number .P74 2007

a Personal name Soylu, Alper.

h Medium Electronic Document

a Title Predictive value of clinical and laboratory variables for vesicoureteral reflux in children.

c Statement of responsibility, etc Alper Soylu, Belde Kasap, Korcan Demir, Mehmet Türkmen, Salih Kavukçu.

c Date of publication, distribution, etc 2007.

b Name of publisher, distributor, etc Springer,

a Place of publication, distribution, etc New York :

a Summary, etc We aimed to determine the predictability of clinical and laboratory variables for vesicoureteral reflux (VUR) in children with urinary tract infection (UTI). Data of children with febrile UTI who underwent voiding cystoureterography between 2002 and 2005 were evaluated retrospectively for clinical (age, gender, fever >= 38.5 degrees C, recurrent UTI), laboratory [leukocytosis, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), pyuria, serum creatinine (S-Cr)] and imaging (renal ultrasonography) variables. Children with VUR (group 1) vs. no VUR (group 2) and children with high-grade (III-V) VUR (group 3) vs. no or low-grade (I-II) VUR (group 4) were compared. Among 88 patients (24 male), 38 had VUR and 21 high-grade VUR. Fever >= 38.5 degrees C was associated with VUR [odds ratio (OR): 7.5]. CRP level of 50 mg/l was the best cut-off level for predicting high-grade VUR (OR 15.5; discriminative ability 0.89 +/- 0.05). Performing voiding cystourethrography based on this CRP level would result in failure to notice 9% of patients with high-grade VUR, whereas 69% of children with no/low-grade VUR would be spared from this invasive test. In conclusion, fever >= 38 degrees C and CRP > 50 mg/l seem to be potentially useful clinical predictors of VUR and high-grade VUR, respectively, in pediatric patients with UTI. Further validation of these findings could limit unnecessary voiding cystourethrography.

a Topical term or geographic name as entry element Urology & Nephrology

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Pediatrics

a Topical term or geographic name as entry element Urinary-Tract-Infection

a Main entry heading Pediatric Nephrology

g Relationship information JUN 2007, Vol 22 Issue 6, p844-848

x International Standard Serial Number 0931041X

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1007/s00467-006-0418-6